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Knee Joint Injections

Knee joint injections, guided by ultrasound, ease swelling and arthritis pain. We can also drain extra fluid from the joint. Given by our board-certified pain doctors at Remix Medical in Houston, TX.

Knee Joint Injections in Houston, Texas

A knee that hurts on stairs, swells after a walk, and wakes you at night is not simply going to be talked out of it. Injecting the joint directly puts medication where the inflammation is, at a fraction of the systemic exposure of oral anti-inflammatories — which matters a great deal if your kidneys or stomach cannot tolerate them.

What is a Knee Joint Injection?

A knee joint injection delivers corticosteroid and local anesthetic into the intra-articular space of the knee, typically under ultrasound guidance to confirm the needle is inside the joint capsule rather than in the surrounding fat.

Guidance matters more than most patients are told. Landmark-only knee injections miss the joint space in a meaningful minority of attempts, particularly in larger knees or when there is little effusion.

StageWhat happens
BeforeYou're positioned, the skin is cleaned and numbed, and live imaging (fluoroscopy or ultrasound) guides the needle
DuringThe medication is placed precisely at inside the knee joint; most people feel pressure more than sharp pain
AfterYou rest briefly and go home the same day — arrange a driver if you received sedation

What It Treats

  • Knee osteoarthritis , particularly during an inflammatory flare
  • Effusion — a swollen, tense knee that limits motion
  • Inflammatory arthritis involving the knee
  • Post-traumatic arthritis following meniscal or ligament injury
  • Knees awaiting arthroplasty where symptom control is needed in the interim

Where It Fits

A steroid injection is a short-to-medium-term intervention. It reliably reduces pain and swelling for weeks to a few months. It does not modify the disease, and repeated high-frequency injections into the same joint are not benign.

For patients wanting longer intervals, the options are viscosupplementation and genicular nerve radiofrequency ablation. For patients not yet ready for replacement, that ladder is often the difference between deferring surgery and scheduling it.

Relief from Knee Pain at Remix Medical

Because Remix Medical is a multispecialty group, your knee injection is dosed with your kidney function and diabetes control in view — not in isolation.

How it's performed

The knee is positioned in slight flexion and the skin is cleansed and anesthetized. Under ultrasound guidance, a needle is advanced into the joint space, most often via a lateral suprapatellar or anterolateral approach. Any effusion may be aspirated first, which both relieves pressure and permits fluid analysis. Corticosteroid combined with local anesthetic is then injected into the joint.

How to prepare

No fasting required. You may drive yourself. Hold anticoagulants only as directed by the prescribing physician. Wear loose clothing or shorts. Notify the office if you have an active infection, fever, or a prosthetic knee.

What to expect after

Ice the knee 20 minutes every 2 to 3 hours for the first day. Avoid high-impact activity and prolonged standing for 48 hours; gentle range of motion is encouraged. A brief post-injection flare in the first 24 to 48 hours is common. Monitor blood glucose closely if diabetic. Report fever, escalating pain, or a hot, red, swollen knee immediately — these suggest infection.

Outcome

Most patients experience meaningful reduction in knee pain and swelling within days, with benefit typically lasting several weeks to a few months. Relief commonly allows progression with strengthening exercises that make the effect more durable.

Frequently asked

Knee Joint Injections questions, answered

What is a knee injection for arthritis?

It's an injection of medication directly into the knee joint to reduce inflammation and pain. Steroid, gel (viscosupplement), and PRP injections are the common types.

Do knee injections hurt?

You'll feel a pinch and some pressure, and the joint may feel full briefly. Most people tolerate it well with only mild, short-lived soreness.

How long do knee injections last?

A steroid injection often helps for weeks to a few months, while gel injections may last longer for some people. Results vary, so they're used as part of a plan with exercise.

How often can I get knee injections?

Steroid injections are usually spaced out, often no more than every few months, to protect the joint. Your doctor sets a safe schedule for your situation.

What should I do after a knee injection?

Take it easy for the rest of the day, then resume normal activity. Call for fever, spreading redness, or severe swelling, which are uncommon but need attention.

SpecialtyPain ManagementTypeProcedureBody locationKnee joint, tibiofemoral joint, suprapatellar pouch, patellofemoral joint, synoviumCPT code20610 (arthrocentesis/injection, major joint, without ultrasound), 20611 (with ultrasound guidance and permanent recording); J-codes billed separately for the corticosteroid administered

Also called Intra-Articular Knee Injection, Knee Steroid Injection, Knee Arthrocentesis, Cortisone Shot Knee

This page is for general education and is not a substitute for medical advice. Whether a given procedure is appropriate depends on your individual evaluation. Contact a Remix Medical clinician to discuss your care.

Updated July 9, 2026. Medically reviewed by Raju Mantena, DO.

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