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Neuroma InjectionUltrasound-guided neuroma injections to quiet a specific painful nerve ending — used for Morton's neuroma, amputation stump pain, and post-surgical nerve pain at Remix Medical in Houston, TX.

Specialty
Pain Management
Type
Procedure
Body location
Peripheral nerve, residual limb, intermetatarsal space, surgical scar, cutaneous nerve branches
CPT code
64455 (injection, anesthetic and/or steroid, plantar common digital nerve — Morton's neuroma); 64450 (injection, other peripheral nerve or branch); 64632 (destruction by neurolytic agent, plantar common digital nerve); 76942 (ultrasound guidance, when reported separately)

Also known as: Morton's Neuroma Injection, Stump Neuroma Injection, Peripheral Nerve Injection, Neuroma Block

Neuroma Injection in Houston, Texas

When a nerve is cut or crushed, it tries to regrow. If it cannot find its way back to its target, the regenerating fibers coil into a disorganized tangle called a neuroma. That tangle fires on its own. Touch it and a bolt of pain shoots down the nerve's territory.

What is a Neuroma Injection?

A neuroma injection places local anesthetic — with or without corticosteroid — directly around the neuroma, typically under ultrasound guidance so the target can be visualized rather than guessed at.

It confirms the neuroma as the pain generator and, in many patients, quiets it for weeks to months. For a well-localized neuroma with reproducible tenderness, this is one of the more satisfying interventions in pain medicine, because the diagnosis is confirmed in real time.

Where Neuromas Form

  • Morton's neuroma — between the metatarsal heads of the forefoot, causing burning pain and the sensation of a pebble in the shoe
  • Amputation stump neuromas — a leading contributor to residual limb pain and to phantom limb pain
  • Post-surgical neuromas — after hernia repair, knee replacement, thoracotomy, or breast surgery
  • Traumatic neuromas — following laceration or crush injury
  • Scar neuromas — where a cutaneous nerve is entrapped in scar tissue

Finding It

Examination is the diagnosis. A well-localized point of exquisite tenderness that, when tapped, produces electric pain radiating along the nerve's distribution — a positive Tinel's sign — is the classic finding. Ultrasound frequently visualizes the neuroma directly as a hypoechoic swelling in the nerve.

If anesthetic placed on that spot abolishes the pain, the question is answered.

Beyond the Injection

When injections provide reliable but short-lived relief, options include radiofrequency ablation of the nerve, cryoablation, chemical neurolysis, or surgical revision. For amputees, neuroma treatment is frequently the missing piece in an otherwise stalled prosthetic rehabilitation.

Precise Relief at Remix Medical

Contact Remix Medical to schedule a consultation with a board-certified pain management physician in Houston.

How it's performed

The neuroma is localized by palpation for a point of maximal tenderness with a positive Tinel's sign, then confirmed with ultrasound, which typically shows a hypoechoic swelling along the nerve. Under ultrasound guidance, a fine needle is advanced adjacent to the neuroma and local anesthetic, with or without corticosteroid, is deposited around it. Immediate abolition of the familiar pain confirms the neuroma as the pain generator.

How to prepare

No fasting required and you may drive yourself for most superficial injections. Hold anticoagulants only as directed by the prescribing physician. Point out the exact spot of maximal tenderness to your physician before the skin is prepped — your localization is the most valuable diagnostic information available.

What to expect after

Expect numbness in the nerve's distribution for several hours. Ice the site 20 minutes every 2 to 3 hours on the first day. Protect a numb foot or limb from injury and pressure until sensation returns. For Morton's neuroma, wear wide, low-heeled shoes. Monitor blood glucose if diabetic. Report fever, spreading redness, or skin breakdown.

Outcome

Immediate abolition of the familiar pain confirms the neuroma as the source. Corticosteroid frequently extends relief for weeks to months. Reliable but short-lived relief identifies candidates for radiofrequency ablation, cryoablation, or surgical revision.

Your physician

Your pain management at Remix Medical.

Every clinician at Remix Medical is board-certified and owns the practice — so the physician in your exam room is the one making decisions about your care.

  • Raju Mantena, DO

    Pain Medicine Physician

    Medical Center — South Freeway · Montrose — Upper Kirby · Pearland

    Board certifiedAccepting newBook

This page is for general education and is not a substitute for medical advice. Whether a given procedure is appropriate depends on your individual evaluation. Contact a Remix Medical clinician to discuss your care.

Updated July 9, 2026.

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