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Kidney Function Testing (eGFR & Creatinine)

A simple blood test shows how well your kidneys filter. It is the first and most important step in finding kidney disease, at Remix Medical in Houston, TX.

If you have diabetes, high blood pressure, or a family history of kidney disease, these two blood tests are how we find out whether your kidneys are struggling — often years before you would feel anything.

What these tests measure

Creatinine is a waste product your muscles make every day. Healthy kidneys clear it from your blood at a steady rate. When kidney function drops, creatinine rises.

On its own, creatinine is a blunt instrument. A muscular 30-year-old and a frail 80-year-old can have the same creatinine and very different kidney function. That is why we calculate eGFR — estimated glomerular filtration rate — which adjusts the creatinine result for your age and sex to estimate how many milliliters of blood your kidneys filter each minute.

What your eGFR means

A normal eGFR is above 90. Below 60, sustained for three months or longer, meets the definition of chronic kidney disease.

  • 90 or above — normal filtration
  • 60 to 89 — mildly reduced; often normal for age
  • 45 to 59 — Stage 3a chronic kidney disease
  • 30 to 44 — Stage 3b
  • 15 to 29 — Stage 4; time to plan for kidney replacement therapy
  • Below 15 — Stage 5, kidney failure

A single low result does not make a diagnosis. Dehydration, a recent illness, or certain medications can push creatinine up temporarily. We look at the trend across repeated tests.

TestWhat it tells us
eGFRHow much filtering capacity remains
Urine albumin (ACR)Whether the filters are leaking protein
CreatinineThe blood marker eGFR is calculated from

What happens at your visit

A standard blood draw. No fasting is required, and results are usually back within a day.

We pair the eGFR with a urine albumin-to-creatinine ratio, because kidney damage and kidney function are two different things. It is entirely possible to have a normal eGFR and significant protein leaking into the urine — that combination changes both your prognosis and your treatment.

Why this matters early

Early chronic kidney disease has no symptoms. By the time swelling, fatigue, or foamy urine appear, substantial function has usually been lost. Testing catches it while there is still a great deal we can do — blood pressure control, SGLT2 inhibitors, ACE inhibitors or ARBs, and medication adjustments that meaningfully slow or halt progression.

How it's performed

A standard venous blood draw measures serum creatinine. The laboratory then calculates estimated glomerular filtration rate (eGFR) using a validated equation that adjusts the creatinine value for age and sex. Remix Medical uses the 2021 CKD-EPI creatinine equation, which does not include a race coefficient. Results are interpreted alongside a urine albumin-to-creatinine ratio, because reduced filtration and structural kidney damage are distinct findings that carry different prognostic weight.

How to prepare

No fasting or special preparation is required. Continue taking your usual medications unless instructed otherwise. Tell your physician if you have recently taken creatine supplements, completed intense exercise, or started a new medication, as each can temporarily affect creatinine levels.

Outcome

An eGFR value that stages kidney function and, tracked over time, reveals whether kidney disease is stable or progressing. Early detection allows blood pressure control, SGLT2 inhibitor therapy, and medication adjustment to meaningfully slow or halt progression before symptoms appear.

Frequently asked

Kidney Function Testing (eGFR & Creatinine) questions, answered

How is kidney function measured?

Mainly with a blood test that calculates your eGFR (an estimate of filtering capacity) and a urine test for albumin. Together they define kidney health.

What is a normal eGFR?

An eGFR of 90 or above is generally normal, and below 60 for three months or more suggests chronic kidney disease. Your doctor reads it with your urine results and history.

What is the difference between creatinine and eGFR?

Creatinine is a waste product measured in the blood, and eGFR is calculated from it to estimate how well your kidneys filter. eGFR is the more useful number for staging.

How often should kidney function be checked?

It depends on your risk, but people with diabetes, high blood pressure, or kidney disease should have it checked regularly, often yearly or more. Tracking the trend matters most.

Why do both a blood and urine test matter for kidneys?

eGFR shows filtering capacity, while urine albumin shows whether the filters are leaking. Either one alone can miss disease, so both are checked together.

SpecialtyNephrology & HypertensionTypeDiagnostic testCPT code82565 (creatinine, blood); 82610 (cystatin C); 82570 (creatinine, other source); 82043 (albumin, urine, quantitative); 80048, 80053 (basic and comprehensive metabolic panel)

Also called eGFR, Estimated Glomerular Filtration Rate, GFR Test, Serum Creatinine, Creatinine Blood Test, Kidney Function Panel, Renal Function Test

This page is for general education and is not a substitute for medical advice. Whether a given procedure is appropriate depends on your individual evaluation. Contact a Remix Medical clinician to discuss your care.

Updated July 9, 2026. Medically reviewed by Uday Khosla, MD.

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